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MS Final Examination – Yuting Xi


Thursday, April 27, 2017 1:00 PM - 3:00 PM

Optofluidic Sensing from Inkjet-Printed Droplets on Diatom Biosilica
We explored an optofluidic sensing mechanism from inkjet-printed droplets on diatom biosilica using surface-enhanced Raman scattering (SERS). Our study revealed a new biosensing strategy that combines the microscopic fluidic flow induced by the droplet evaporation and the photonic crystal effects of diatom frustules, which can provide an ultra-sensitive, cost-effective biosensing technology with reduced analyte consumption enormous improvement of detection limit by 106×. Different than the traditional analyte dispensing method using pipette, inkjet printing technology not only minimizes the analyte consumption and prevents coffee rings, but also facilitates significant molecule accumulation on the hydrophilic surface of the diatom frustule during the evaporation process of sub-nanoliter volume droplets, called the evaporation-induced spontaneous flow effect. We achieved single-molecule-level detection of Rhodamine 6G (R6G) and label-free Trinitrotoluene (TNT) sensing at 10-12 M in aqueous solution.

Major Advisor: Alan Wang
Committee: Larry Cheng
Committee: Matthew Johnston
GCR: Zhenxing Feng


Kelley Engineering Center (campus map)
4107
Calvin Highes
1 541 737 3168
Calvin.Hughes at oregonstate.edu
Sch Elect Engr/Comp Sci
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